Steroid 5alpha-reductase inhibitory activity and hair regrowth effects of an extract from Boehmeria nipononivea |
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| Authors: | Shimizu K Kondo R Sakai K Shoyama Y Sato H Ueno T |
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| Affiliation: | Department of Forest Products, Faculty of Agriculture, Kyushu University, Fukuoka, Japan. |
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| Abstract: | The acetone extract of Boehmeria nipononivea showed both potent 5alpha-reductase inhibitory activity and hair regrowth promotion effects on mice. 5alpha-Reductase inhibitory activity-guided fractionation led to six active fatty acids: alpha-linolenic, linoleic, palmitic, elaidic, oleic and stearic acids. The extract of B. nipononivea, and alphalinolenic, elaidic and stearic acids exhibited a hair regrowth effect. |
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