| Sibp：KM小鼠的生长繁殖及其若干生物学特性研究 |
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| 引用本文： | 潘振业,朱帜,王汉荣,周玮,姚健,徐志刚. Sibp：KM小鼠的生长繁殖及其若干生物学特性研究[J]. 中国实验动物学报, 1995, 0(1) |
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| 作者姓名： | 潘振业 朱帜 王汉荣 周玮 姚健 徐志刚 |
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| 作者单位： | 卫生部上海生物制品研究所 |
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| 摘 要： | 本文按国际上远交群小鼠的遗传监测和控制的要求，对Ｓｉｂｐ：ＫＭ小鼠进行育种繁殖、遗传背景和生物学特性等多方面的研究。统计分析该小鼠繁殖性能，绘制了生长曲线。测定２４个生化标志基因位点，其中１１个位点呈多态型，平均杂合率为０．２０９。该小鼠下颌骨形态分析的部分判别函数值（占４４％）超过均值±２ＳＤ，呈弥散分布。该小鼠Ｈ－２组织相容合体，具有１０种Ｉ类私有抗原，１７种表现型。此外还测定该小鼠形态数据、部分血液学数据和整体分析，为Ｓｉｂｐ：ＫＭ小鼠推广应用提供技术数据。
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| 关 键 词： | Sibp：KM小鼠，遗传背景，生物学特性 |
Study on the Biological Characteristics of Sibp : KM Mouse |
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| Pan Zhenye,et al. Study on the Biological Characteristics of Sibp : KM Mouse[J]. Acta Laboratorium Animalis Scientia Sinica, 1995, 0(1) |
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| Authors: | Pan Zhenye et al |
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| Affiliation: | Shanghai. Institute of Biological Products of the Ministry of Health |
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| Abstract: | he genetic background, reproductive performance and biologicalcharacteristics were studied on outbred stock of Sibp : KM mouse. Inaccordance with The Cenetic Control Measures in Outbred Stock, thestatistic analysis of the reproductive performance and the growth curvewere made.24 biochemical genetic markers were tested.The average hetero-zygosity was found to be 0.209. The mandible morphimetric analysis reve-aled that 44% of the DF values exceeded 2SD. H-2 polymorphism wasalso studied, 10 class I private antigens with 17 phenotypes were found inthis colony. Morphometric data, including body length, ulna length, bodyweight. were measured,and basic hematological data and total body analy-sis were tested. |
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| Keywords: | Sibp : KM Mouse Genetic background Biologicalcharacteristics |
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