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淋病奈瑟菌粘附性质粒的研究
引用本文:张学英,崔英顺,肖洋,王胜春,史红艳,关显智.淋病奈瑟菌粘附性质粒的研究[J].微生物学杂志,2001,21(4):60-61.
作者姓名:张学英  崔英顺  肖洋  王胜春  史红艳  关显智
作者单位:1. 吉林大学,基础医学院病原生物学教研室,吉林,长春,130021
2. 吉林省安图县第二人民医院,吉林,安图,133600
3. 长春医学专科学校,吉林,长春,130000
摘    要:从1株临床分离的淋病奈瑟菌(N.gonorrheae,Ng)分别检测出耐氨苄青霉素(AMPr)及四环素(TCr)的2种质粒(R质粒),其分子量分别为25.2 Mu和4.5 Mu.进一步研究发现,编码TCr的质粒也编码普通菌毛,因而与其粘附性有关.消除此R质粒不但细菌的TCr消失,电镜下观察其菌毛几乎全部消失,其粘附性也显著降低,故此R质粒也被确认为是粘附性质粒(Adh质粒).

关 键 词:淋病奈瑟菌  粘附性  质粒
文章编号:1005-7021(2001)04-0060-02
修稿时间:2001年9月26日

STUDY ON ADHERENCE PLASMIDS IN Neisseria gonorrheae
Zhang Xueying et al..STUDY ON ADHERENCE PLASMIDS IN Neisseria gonorrheae[J].Journal of Microbiology,2001,21(4):60-61.
Authors:Zhang Xueying
Abstract:Two R plasmids encoding with tetracycline resistance TC r of MW 25.2 Mu and 4.5 Mu ampicillin resistance AMP r were detected from a Neisseria gonorrheae strain N.g 141 respectively. The R plasmids were found to encode ordinary pili as well as adherence of bacteria to urinary epithelia in further study. After curing the plasmids both of TC r and adherence disappeared, observation under electromicroscope no pili were found. These indicated that the R plasmids were adherence plasmids.
Keywords:Neisseria gonorrheae    adherence plasmid  
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