Production of swainsonine from Metarhizium anisopliaein stirred-tank and air-lift reactors |
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Authors: | C Tamerler-Yildir MW Adlard T Keshavarz |
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Institution: | (1) Biotechnology Division, Department of Biosciences, University of Westminster, 115 New Cavendish Street, London, W1M 8JS, UK |
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Abstract: | Growth of Metarhizium anisopliaein modified starch-casein medium produced 61, 50, and 58 mg swainsonine/l when cultured in shaken flasks, stirred-tank and air-lift reactors respectively. Over approximately 45 h, the maximum swain-sonine specific productivity was 0.47 mg/g.h in a stirred tank reactor and 0.32 mg/g.h in an air-lift reactor. After 120 h, increasing broth viscosity was encountered in the latter fermenter. |
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