Evaluation of genetic damage induced by 8-ethoxycaffeine in Drosophila melanogaster |
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Authors: | N Xamena A Creus R Marcos |
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Institution: | Departamento de Genética, Facultad de Ciencias, Universidad Autónoma de Barcelona, Bellaterra Spain |
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Abstract: | The methylated oxypurine, 8-ethoxycaffeine (EOC), was tested for the induction of genetic damage in Drosophila melanogaster. Sex-linked recessive lethals, sex-chromosome loss and tanslocation induction were studied following treatment of adult males, using a feeding technique. Our results show that EOC induces sex-chromosome loss and translocations between the second and third chromosomes, but is unable to induce point mutations in male germ cells under our conditions of testing. |
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Keywords: | Correspondence addressee |
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