SAQC: SNP Array Quality Control |
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Authors: | Hsin-Chou Yang Hsin-Chi Lin Meijyh Kang Chun-Houh Chen Chien-Wei Lin Ling-Hui Li Jer-Yuarn Wu Yuan-Tsong Chen Wen-Harn Pan |
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Institution: | (1) Institute of Statistical Science, Academia Sinica, Taipei, 115, Taiwan;(2) Institute of Biomedical Sciences, Academia Sinica, Taipei, 115, Taiwan |
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Abstract: | Background Genome-wide single-nucleotide polymorphism (SNP) arrays containing hundreds of thousands of SNPs from the human genome have
proven useful for studying important human genome questions. Data quality of SNP arrays plays a key role in the accuracy and
precision of downstream data analyses. However, good indices for assessing data quality of SNP arrays have not yet been developed. |
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