Denaturing gradient gel electrophoresis of neonatal intestinal microbiota in relation to the development of asthma |
| |
Authors: | Carl Vael Liesbeth Vanheirstraeten Kristine N Desager Herman Goossens |
| |
Institution: | (1) Department of Microbiology, University of Antwerp, Antwerp, Belgium;(2) Department of Pediatrics, University of Antwerp, Antwerp, Belgium |
| |
Abstract: | Background The extended 'hygiene hypothesis' suggests that the initial composition of the infant gut microbiota is a key determinant
in the development of atopic disease. Several studies have demonstrated that the microbiota of allergic and non-allergic infants
are different even before the development of symptoms, with a critical time window during the first 6 months of life. The
aim of the study was to investigate the association between early intestinal colonisation and the development of asthma in
the first 3 years of life using DGGE (denaturing gradient gel electrophoresis). |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|