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Rough sheets and smooth tubules
Authors:Shibata Yoko  Voeltz Gia K  Rapoport Tom A
Affiliation:Howard Hughes Medical Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
Abstract:The endoplasmic reticulum (ER) has distinct morphological domains composed of sheets and tubules, which differ in their characteristic membrane curvature. Key proteins may drive the formation of these structural morphologies, which in turn could generate the rough and smooth functional domains of the ER.
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