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Molecular interactions of acute phase serum amyloid A: Possible involvement in carcinogenesis
Authors:M. A. Vlasova  S. A. Moshkovskii
Affiliation:(1) Orekhovich Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Pogodinskaya ul. 10, 119121 Moscow, Russia
Abstract:Acute phase serum amyloid A (A-SAA) is a well-known marker of inflammation. The present review summarizes data on the regulation of A-SAA expression, signaling pathways which it is involved in, its effects, and possible influences on progression of malignant tumors.
Keywords:inflammation  malignant tumor  serum amyloid A  NFκ  B  matrix metalloproteinase
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