From mouth to anus: Functional and structural relevance of enteric neurons in the Drosophila melanogaster gut |
| |
| Affiliation: | 1. Department of Molecular Biopharmacy and Genetics, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai, Japan;2. PRESTO, Japan Science and Technology Agency, Tokyo, Japan;1. Department of Neurobiology and Genetics, Theodor-Boveri-Institute, Biocenter, University of Würzburg, D-97074 Würzburg, Germany;2. Department of Biology, University of Konstanz, D-78464 Konstanz, Germany;3. HHMI Janelia Research Campus, 19700 Helix Drive, Ashburn, VA 20147, USA;4. Department of Genetics, University of Leipzig, D-04103 Leipzig, Germany;1. Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, ON M5S 3B2, Canada;2. Child and Brain Development Program, Canadian Institute for Advanced Research, Toronto, ON M5G 1ZB, Canada;1. The Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK;2. Laboratory of Molecular Biology, NIMH, 35 Convent Drive, MSC 4035, Bethesda, MD 20892-4035, USA;1. National Creative Research Initiative Center for Symbiosystem, School of Biological Sciences, Seoul National University, Seoul 151-742, South Korea;2. Department of Life Science, Ewha Womans University, Seoul 120-750, South Korea;3. College of Health Science, Ewha Womans University, Seoul 120-750, South Korea |
| |
| Abstract: | The intestinal tract is the main organ involved in host nutritional homeostasis. Intestinal function in both vertebrates and invertebrates is partly controlled by enteric neurons that innervate the gut. Though anatomical and functional aspects of enteric neurons are relatively less characterized in Drosophila than in large insects, analyses of the role of the enteric neurons in flies have remarkably progressed in the last few years. In this review, we first provide a summary of the structure and function of the Drosophila intestine. We then discuss recent studies of the structure and function of enteric neurons in Drosophila melanogaster. |
| |
| Keywords: | Enteric neurons Peritrophic matrix |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
