In-vivo expression of a C-type RNA virus in rat ventral prostate epithelial cells. |
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Authors: | K M Anderson M Rubenstein T M Seed |
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Affiliation: | 1. Oncology Laboratory, Department of Medicine, Rush-Presbyterian-St. Luke''s Medical Center, Chicago, Illinois 60612, USA;2. Department of Biochemistry, Rush-Presbyterian-St. Luke''s Medical Center, Chicago, Illinois 60612, USA;3. Division of Biological and Medical Research, Argonne National Laboratory, Argonne, Illinois 60439 USA |
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Abstract: | During evaluation of a procedure for separating rat ventral prostate epithelial from connective tissue cells, isolated fractions were examined by transmission electron microscopy. Characteristic C-type RNA viruses were seen budding from or in close proximity to the plasma membranes of isolated epithelial cells. Dissociation of rat prostate cells and concentration of the epithelial fraction facilitated detection of this virus. |
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