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RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes
Authors:Joel Johansson  Mate Naszai  Michael C Hodder  Karen A Pickering  Bryan W Miller  Rachel A Ridgway  Yachuan Yu  Pascal Peschard  Saskia Brachmann  Andrew D Campbell  Julia B Cordero  Owen J Sansom
Institution:1. Cancer Research UK Beatson Institute, Glasgow G61 1BD, UK;2. Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, UK;3. McGill University, Montréal, Quebec, Canada;4. Novartis Institutes for Biomedical Research, Basel, Switzerland
Abstract:
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  • Keywords:Ral GTPases  Frizzled-7  Wnt signaling  intestinal stem cells  regeneration  Wnt signalosome  receptor internalization  intestinal homeostasis  stem cell dynamics
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