Sequencing of porcine enterovirus groups II and III reveals unique features of both virus groups |
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Authors: | Krumbholz Andi Dauber Malte Henke Andreas Birch-Hirschfeld Eckhard Knowles Nick J Stelzner Axel Zell Roland |
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Institution: | Institut für Virologie, Klinikum der Friedrich-Schiller-Universit?t, 07745 Jena, Germany. |
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Abstract: | The molecular classification of the porcine enterovirus (PEV) groups II and III was investigated. The sequence of the almost complete PEV-8 (group II) genome reveals that this virus has unique L and 2A gene regions. A reclassification of this group into a new picornavirus genus is suggested. PEV group III viruses are typical enteroviruses. They differ from other enteroviruses by a prolonged stem-loop D of the 5'-cloverleaf structure. |
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