Choroidal folds in association with optic disc drusen

Choroidal folds are undulations in Bruch's membrane, the retinal pigment epithelium and possibly the outer retina. They can result from any intra- or extraocular process that induces sufficient compressive stress within the choroid, Bruch's membrane and retina to force these tissues to buckle. Numerous ocular as well as systemic conditions have been associated with choroidal fold formation. Presented for discussion is a patient with unilateral choroidal folds and optic disc drusen. Arguments both for and against a direct association between the two conditions are made. Emphasis is placed on the differential diagnosis, clinical evaluation, etiology and management of choroidal folds.