Plasticizers as contaminants in high-purity solvents: a potential source of interference in biological analysis. |
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| Authors: | R A DeZeeuw J H Jonkman F J Van Mansvelt |
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| Affiliation: | Laboratory for Pharmaceutical and Analytical Chemistry, State University, Groningen, The Netherlands 8004 |
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| Abstract: | Cap liners were found to be a major source of plasticizer contamination of high-purity extraction solvents. Plasticizer concentrations found ranged from 0.1–5 ppm; this can produce substantial interference in biological analysis because of the rather high concentration factors obtained in the final extracts. |
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