Structure and function of the homeotic gene complex (HOM-C) in the beetle, Tribolium castaneum |
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Authors: | Beeman R W Stuart J J Brown S J Denell R E |
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Institution: | US Grain Marketing Research Laboratory, USDA, Manhattan, KS 66502, USA. |
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Abstract: | The powerful combination of genetic, developmental and molecular approaches possible with the fruit fly, Drosophila melanogaster, has led to a profound understanding of the genetic control of early developmental events. However, Drosophila is a highly specialized long germ insect, and the mechanisms controlling its early development may not be typical of insects or Arthropods in general. The beetle, Tribolium castaneum, offers a similar opportunity to integrate high resolution genetic analysis with the developmental/molecular approaches currently used in other organisms. Early results document significant differences between insect orders in the functions of genes responsible for establishing developmental commitments. |
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