首页 | 本学科首页   官方微博 | 高级检索  
     


Self-assembled synthesis, characterization and antimicrobial activity of zinc(II) salicylaldimine complexes
Authors:Ma?gorzata T. Kaczmarek  El?bieta Ho?derna-K?dzia
Affiliation:a Faculty of Chemistry, Adam Mickiewicz University, Grunwaldzka 6, 60-780 Poznań, Poland
b Institute of Medicinal Plants, Libelta 27, 61-707 Poznań, Poland
Abstract:One-pot metal promoted reactions between salicylaldehyde and 4-methyl-1,3-phenylenediamine in the presence of metal salts acting as template agents yield zinc(II) salicylaldimine complexes containing N,N′-bis(salicylidene)-4-methyl-1,3-phenylenediamine (H2L) as a result of the [2 + 1] Schiff base condensation. The complexes of formula [Zn(HL)Cl(H2O)2] · C2H5OH and [Zn(H2L)2Cl(NO3)(H2O)] · CH3OH were characterized as powder solids and in solution by spectroscopic methods (IR, 1H and 13C NMR, FAB-MS, ESI-MS, UV-Vis), thermogravimetric and elemental analysis, potentiometry, and tested for antimicrobial activity against Staphylococcusaureus in a minimum inhibitory concentration (MIC) experiment. In these two powder solid species, the salicylaldimine, formed in a self-assembly process, acts in two different coordination modes: as monodeprotonated bidentate chelator with an N,O donor set or as a neutral monodentate using exclusively oxygen as the donor atom without involving the nitrogen atoms in the coordination. However, crystals of these two complexes are isomorphous, with 1:2 metal:ligand stoichiometry, and display the latter, relatively rare coordination pattern. In solution, the presence of a 1:1 complex of monodeprotonated state is only detected. The complexes exhibit antimicrobial activity against S.aureus.
Keywords:Zinc(II) complexes   Salicylaldimines   Self-assembly   Structure   Speciation   Antimicrobial activity
本文献已被 ScienceDirect 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号