|
|||||
|
|
Antimicrobial activity of ethylenediaminedisuccinate metal complexes |
|
| Authors: | Costa Natália J S Bombardieri Cíntia R Kuribayashi Juliana S de Camargo Maristela M Andrade Leandro H Kagohara Edna Espósito Breno P |
| Institution: | 1. University of S?o Paulo, Institute of Chemistry, Av. Lineu Prestes 748 sala 1265, 05508‐000, S?o Paulo, Brazil (phone: +55‐11‐3091‐2181;2. fax: +55‐11‐3815‐5579);3. University of S?o Paulo, Institute of Biomedical Sciences, Av. Lineu Prestes 2415, 05508‐000, S?o Paulo, Brazil |
| Abstract: | It is shown that metal complexes of the biodegradable ligand ethylenediaminedisuccinic acid (edds) present antimicrobial activity towards fungi and bacteria. Cd(edds)], in particular, is more toxic than free Cd2+ to Aspergillus niger, behaving as a 'Trojan Horse' in the facilitated delivery of the toxic metal into the fungus. |
| Keywords: | Ethylenediaminedisuccinate complexes ‘Trojan Horse’ Cadmium complexes Antimicrobial activity |
| 本文献已被 PubMed 等数据库收录！ | |