Structural deformation upon protein-protein interaction: A structural alphabet approach |
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| Authors: | Juliette Martin Leslie Regad Hélène Lecornet Anne-Claude Camproux |
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| Affiliation: | 1.Equipe de Bioinformatique Génomique et Moléculaire,INSERM UMRS726/Université Denis Diderot Paris 7,Paris,France;2.Unité Mathématiques Informatique et Génome UR1077,INRA,Jouy-en-Josas,France |
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| Abstract: | Background In a number of protein-protein complexes, the 3D structures of bound and unbound partners significantly differ, supporting the induced fit hypothesis for protein-protein binding. |
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