Cloning and characterization of the lytB gene of Campylobacter jejuni |
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| Authors: | Marc M.S.M Wö sten,Ed E Ishiguro,Bernard A.M van der,Zeijst |
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| Affiliation: | Unitédes Toxines Microbiennes, CNRS URA1858, Institut Pasteur, 28 rue du Dr. Roux, 75724 Paris Cedex 15, France;Laboratoire de Génétique Moléculaire des Toxines, CNRS URA 1858, Institut Pasteur, 28 rue du Dr. Roux, 75724 Paris Cedex, France |
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| Abstract: | LytB of Escherichia coli is an essential gene involved in penicillin tolerance and the stringent response. The lytB gene of Campylobacter jejuni was cloned and characterized. It could complement a temperature-sensitive E. coli lytB mutant. The C. jejuni lytB gene encodes a protein of 277 amino acids that has 34, 36 and 40% amino acid identity with the LytB proteins of E. coli, Haemophilus influenzae, and Synechocystis sp. PCC6803, respectively. The lytB gene is situated between the aroA gene and a gene that encodes ribosomal protein S1. |
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| Keywords: | Clostridium perfringens iota toxin Clostridium spiroforme toxin Anthrax toxin Bacillus anthracis |
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