| DNA序列基于k-字的数值刻画及其应用 |
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| 引用本文： | 刘俊宏,李 春. DNA序列基于k-字的数值刻画及其应用[J]. 生物信息学, 2013, 11(2): 142-145 |
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| 作者姓名： | 刘俊宏 李 春 |
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| 作者单位： | 渤海大学数理学院,辽宁锦州,121013 |
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| 基金项目： | 国家自然科学基金项目(项目编号：11171042)辽宁省高等学校杰出青年学者成长计划(项目编号：LJQ2011122) |
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| 摘 要： | 借助DNA序列中k-字的频数,将序列转化成一个340维向量,进而计算物种间的进化距离。作为应用:分别以15个物种的β球蛋白基因、13种汉坦病毒的S片段以及26个闭壳龟线粒体基因为例,构建系统发生树,所得结果与前人的结论一致,说明了该方法的有效性。
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| 关 键 词： | k-字 340维向量 系统发生树 |
| 收稿时间： | 2012-10-20 |
| 修稿时间： | 2012-11-22 |
A numerical characterization of DNA sequences based on k-words and its application |
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| LIU Jun-hong and LI Chun. A numerical characterization of DNA sequences based on k-words and its application[J]. Chinese Journal of Bioinformatics, 2013, 11(2): 142-145 |
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| Authors: | LIU Jun-hong and LI Chun |
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| Affiliation: | (Department of Mathematics, Bohai University, Liaoning Jinzhou 121013, China ) |
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| Abstract: | By means of the frequencies of k-words, the DNA sequence is transformed into a 340-D vector, and then the evolutional distance is obtained. The proposed measure is used to construct phylogenetic trees on three separate sets ： the full β-globin genes of 15 species, the S segments of 13 hantaviruses and 26 Cuora mitochodriona genes. The results are consistent with those of previous analyses, which illustrates the utility of the approach. |
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| Keywords: | k-words 340-D Vector Phylogenetic Trees |
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