Translocation between chromosome 7 and chromosome 22, t(7;22)(p22;q12), in a patient with chronic myelocytic leukemia |
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| Authors: | Gösta Gahrton Kristina Friberg Lore Zech |
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| Institution: | (1) Karolinska Institute, Department of Medicine, Section of Oncology and Hematology, Huddinge Hospital, Huddinge, Sweden;(2) Institute of Medical Cell Genetics, Karolinska Institute, Stockholm, Sweden;(3) Department of Medicine, Huddinge University Hospital, S-14186 Huddinge, Sweden |
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| Abstract: | Summary A 46-year-old man with chronic myelocytic leukemia had a new variant translocation between chromosome 22 and chromosome 7 in bone marrow cells. No involvement of chromosome 9 was seen. The patient entered blastic transformation within half a year, by which time he had acquired an isochromosome 17 in addition to the variant translocation. |
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