Enzymatic Synthesis and Antioxidant Properties of <Emphasis Type="SmallCaps">L</Emphasis>-Ascorbyl Oleate and <Emphasis Type="SmallCaps">L</Emphasis>-Ascorbyl Linoleate期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Enzymatic Synthesis and Antioxidant Properties of L-Ascorbyl Oleate and L-Ascorbyl Linoleate

Authors:	Qing-Xun?Song,Dong-Zhi?Wei author-information" > author-information__contact u-icon-before" > mailto:dzhwei@ecust.edu.cn" title=" dzhwei@ecust.edu.cn" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Wen-Yu?Zhou,Wei-Qin?Xu,Sheng-Li?Yang

Affiliation:	(1) State Key Laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai, 200237, P.R. China;(2) Shanghai Research Center of Biotechnology, Chinese Academy of Sciences, P.R. China

Abstract:	L-Ascorbyl oleate and L-ascorbyl linoleate were synthesized by an immobilized lipase from Candida antarctica with yields of 38% and 44%, respectively. L-Ascorbyl oleate was stable in sterile culture medium over 12 h at 37 °C but L-ascorbyl linoleate degraded by 17%. Ascorbyl oleate had a better protective effect on human umbilical cord vein endothelial cells treated with H₂O₂ than of L-ascorbic acid-2-phosphate-6-palmitate (Asc2P6P).Revisions requested 21 July 2004/26 August 2004; Revisions received 20 August 2004/27 September 2004

Keywords:	antioxidant font-variant:small-caps" >L-ascorbyl linoleate font-variant:small-caps" >L-ascorbyl oleate immobilized lipase reactive oxygen species
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