Engineering a DNA damage response without DNA damage |
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| Authors: | ManTek Yeung Daniel Durocher |
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| Affiliation: | (1) Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University Avenue, Toronto, ON, M5G 1X5, Canada;(2) Department of Molecular Genetics, University of Toronto, Toronto, ON, M5S 1A8, Canada; |
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| Abstract: | Recent work has achieved the feat of activating the DNA damage checkpoint in the absence of DNA damage, revealing the importance of protein-chromatin associations for the activation, amplification and maintenance of the DNA damage response. |
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