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Antigen adsorbed calcium phosphate nanoparticles stimulate both innate and adaptive immune response in fish, Labeo rohita H |
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| Authors: | Behera Truptimayee Swain Priyabrat |
| Institution: | Fish Health Management Division, Central Institute of Freshwater Aquaculture, Kausalyaganga, Bhubaneswar 751 002, Orissa, India |
| Abstract: | Calcium phosphate nanoparticles as an antigen/protein delivery was explored in a fish model Labeo rohita H. S-layer protein (of Aeromonas hydrophila) adsorbed on nano sized calcium phosphate particles elicited both innate and adaptive immune parameters which persisted up to 63 days of post immunization through parenteral immunization and gave cross protections. |
| Keywords: | Antigen Adjuvant Adaptive immunity Aeromonas hydrophila Calcium phosphate Fish Innate immunity Nanoparticle Parenteral immunization S-layer protein |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |