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Calcium and phosphate metabolism in uranyl nitrate-induced acute renal failure
Authors:V Stefanovi?  M A Ivi?  S Strahinji?
Affiliation:Institute of Nephrology and Hemodialysis, Faculty of Medicine, Nis, Yugoslavia.
Abstract:Plasma calcium regulation in uranyl nitrate-treated dogs was studied. A discrete hypercalcemia was observed without significant changes in the level of plasma ionized calcium. Serum phosphate increased markedly following uranyl nitrate treatment. A sharp rise of iPTH was demonstrated. Uranyl nitrate-induced acute renal failure in dogs was found to be a useful model for studying the mechanisms regulating calcium and phosphate metabolism.
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