Differential expansion of highly repeated DNA sequences in the swine subgenomes |
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| Authors: | M Pita P GarcÍa-Casado M A Toro and J Gosálvez |
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| Institution: | Unidad de Genética, Departamento de Biología, Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain;;Departamento de Reproducción Animal, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Madrid, Spain;;Departamento de Mejora Genética Animal, Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Madrid, Spain |
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| Abstract: | Differences in highly repeated DNA sequences among three swine breeds genomes were detected by means of whole‐comparative genomic hybridization (W‐CGH). The results showed that Duroc, Iberian and Landrace/Large White breeds share similar DNA sequences in their centromeric regions, but the number of copies of the highly repeated DNA sequences building the blocks of heterochromatin in the metacentric chromosomes is differentially expanded among them. That is not the case in the acrocentric subgenome where the chromosomes share similar sequence composition and number of copies among the three breeds in the centromeric regions. The highly repeated DNA sequences in the chromosome Y also displayed differences among the breeds studied. The reported results are discussed in the light of the possible evolutionary tendencies of these particular DNA sequences. |
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| Keywords: | Comparative genomic hybridization highly repeated DNAs swine genome |
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