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1H, 13C, and 15N resonance assignments of FK506-binding domain of Plasmodium falciparum FKBP35
Authors:Cong Bao Kang  Hong Ye  Hye Rim Yoon  Ho Sup Yoon
Institution:(1) School of Biological Science, Nanyang Technological University, 60 Nanyang Drive, Singapore, 637665, Singapore
Abstract:The immunosuppressant FK506 binds Plasmodium falciparum FK-506 binding protein 35 (PfFKBP35) and shows anti-malarial activity. To understand molecular mechanism of the drug on the parasite, we have done NMR studies. Here, we report the assignment of FK506-binding domain of PfFKBP35.
Keywords:Plasmodium           falciparum            FK506  FKBP  Heteronuclear NMR
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