1H, 13C, and 15N resonance assignments of FK506-binding domain of Plasmodium falciparum FKBP35 |
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Authors: | Cong Bao Kang Hong Ye Hye Rim Yoon Ho Sup Yoon |
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Institution: | (1) School of Biological Science, Nanyang Technological University, 60 Nanyang Drive, Singapore, 637665, Singapore |
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Abstract: | The immunosuppressant FK506 binds Plasmodium falciparum FK-506 binding protein 35 (PfFKBP35) and shows anti-malarial activity. To understand molecular mechanism of the drug on the
parasite, we have done NMR studies. Here, we report the assignment of FK506-binding domain of PfFKBP35. |
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Keywords: | Plasmodium falciparum FK506 FKBP Heteronuclear NMR |
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