A new screening method for investigating microbial interactions |
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| Authors: | TW MacFarlane HC Makrides |
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| Institution: | Oral Microbiology Unit, Department of Oral Medicine and Pathology, Glasgow Dental Hospital and School, 378 Sauchiehall Street, Glasgow G2 3JZ, UK |
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| Abstract: | Interactions among Candida albicans, Staphylococcus aureus and Escherichia coli were investigated using a screening system in which test micro-organisms were incorporated in agar discs and effector micro-organisms in fluid growth media. Total as well as partial inhibition of test micro-organisms was observed in agar discs when these were incubated in broths containing effector micro-organisms. The ratio of numbers of test to effector micro-organisms was found to be of importance in the inhibition effect. The technique was found to be cheap, simple and versatile. |
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