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Amino acid metabolism in hepatocytes isolated from lactating rats
Authors:Loranne Agius
Affiliation:Department of Clinical Biochemistry and Metabolic Medicine, University of Newcastle upon Tyne, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, NE1 4LP, U.K.
Abstract:Parenchymal hepatocytes isolated from lactating rats had similar rates of amino acid incorporation into protein, but increased rates of urea formation compared to hepatocytes from non-lactating rats. The increased urea formation may be due to increased amino acid transport and degradation. The liver contributes to the increased utilization of amino acids during lactation.
Keywords:Lactation   Hepatocyte   Amino acid metabolism   (Rat)
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