Amino acid metabolism in hepatocytes isolated from lactating rats |
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Authors: | Loranne Agius |
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Affiliation: | Department of Clinical Biochemistry and Metabolic Medicine, University of Newcastle upon Tyne, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, NE1 4LP, U.K. |
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Abstract: | Parenchymal hepatocytes isolated from lactating rats had similar rates of amino acid incorporation into protein, but increased rates of urea formation compared to hepatocytes from non-lactating rats. The increased urea formation may be due to increased amino acid transport and degradation. The liver contributes to the increased utilization of amino acids during lactation. |
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Keywords: | Lactation Hepatocyte Amino acid metabolism (Rat) |
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