肠内营养在直肠癌术后急性放射性肠炎中的临床应用研究

目的:研究肠内营养在直肠癌术后急性放射性肠炎中的临床应用。方法:选择2012年7月~2013年7月在我院接受治疗的104例直肠癌手术后发生急性放射性肠炎的患者作为研究对象。依照数字法随机分成观察组(51例)和对照组(53例)。对照组予以(半)流质食物,观察组则予以能全力肠内营养支持治疗。分别在治疗前以及治疗后7d测定血生化、营养以及电解质指标。结果:经7d治疗后,观察组的前白蛋白(PA)、白蛋白(Alb)、视黄醇结合蛋白(RBP)及体重(BW)水平均显著高于治疗前以及对照组,C反应蛋白(CRP)显著低于对照组,差异均有统计学意义(均P0.05);但两组治疗后的总蛋白(TP)水平差异无统计学意义(P0.05);两组治疗前后的谷丙转氨酶(ALT)、血清碱性磷酸酶(AKP)、凝血酶原时间(PT)、胆红素(BIL)、尿素氮(BUN)、肌酐(Cr)及血糖(Glu)等血生化指标以及钾离子(K+)、钠离子(Na+)、氯离子(Cl-)、钙离子(Ca2+)等电解质指标的差异均无统计学意义(均P0.05)。结论:通过肠内营养治疗直肠癌手术后发生的放射性肠炎,可改善患者的营养状况,效果显著,值得推广。

Clinical Application Research of Enteral Nutrition for Acute RadioactiveEnteritis in Postoperative Patients of Rectal Cancer

Objective:To study clinical application research of enteral nutrition for acute radioactive enteritis of postoperativerectal cancer.Methods:104 cases of postoperative rectal cancer patients with acute radioactive enteritis fromJuly 2012 to July 2013 wereselected as the research object. They were divided into the observation group (51 cases) and control group (53 cases) according to therandomnumber method. The control group was given (half) liquid foods; the observation group was given fully enteral nutrition supporttreatment. Before and 7 d after treatment, blood biochemical indicators, nutrition condition index and electrolyte indicators were tested.Results:After 7d treatment, the PA, Alb, RBP and BW levels of the observation group were significantly higher than before treatmentand than those of the control group, the level of CRP was significantly lower than that of the control group, the difference had statisticalsignificance (P<0.05). But TP level difference of the two groups after treatment with no statistical significance (P>0.05). In the twogroups, ALT, AKP, PT, BIL, BUN, Cr and Glu blood biochemical indexes and K+, Na+, Cl- and Ca2+ electrolyte indexes'' had no statisticalsignificant differences before and after treatment (P>0.05).Conclusion:Enteral nutrition treatment for radioactive enteritis that occurs afterrectal cancer surgery can improve the nutritional status of patients. It had obvious effect, which is worth of promotion.