慢性阻塞性肺疾病急性加重对患者生活质量的影响

目的:探讨慢性阻塞性肺疾病急性加重对患者生活质量的影响。方法:以中国中医科学院广安门医院呼吸科长期慢病管理计划中确诊的慢性阻塞性肺疾病患者为研究对象,记录其在2013年1月至12月间发生的慢性阻塞性肺疾病急性加重事件的情况,并采用面对面访谈式问卷调查方法,在2013年12月对患者进行肺疾病评估测试、焦虑自评量表评分及抑郁自评量表评分,以探讨急性加重发生对患者健康的影响。结果:504例慢性阻塞性肺疾病患者中,过去1年间220例(43.7%)有急性加重发作,其CAT评分、SAS评分、SDS评分均高于未发生急性加重患者,差异均有统计学意义(P0.05)。急性加重发作患者中,66.4%的生活质量均受到中等程度及以上影响,高于无急性加重发生组(52.1%),差异有统计学意义(P0.05)。此外,有急性加重发作的患者合并焦虑和/或抑郁状态的患病率也高于无急性加重发作的患者,差异有统计学意义(P0.05)。结论:慢性阻塞性肺疾病急性加重对患者生活质量、精神状态均可能产生不利影响。

Impact of Chronic Obstructive Pulmonary Disease Exacerbation on Patients'Quality of Life

Objective:To investigate the impacts of acute exacerbation of chronic obstructive pulmonary disease on patients'' qualityof life.Methods:Patients with chronic obstructive pulmonary disease (COPD) were managed in the department of respiration ofGuang''anmen Hospital of China Academy of Chinese medical sciences. The occurrence of acute exacerbation were recorded from Januaryto December in 2013. In December 2013, patients were surveyed by face-to-face interview administration questionnaire. Pulmonarydisease assessment test, self rating anxiety scale and self rating depression scale were used to assess the patients''s health status.Results:Of 504 patients with COPD, 220 cases (43.7%) suffered acute exacerbation during the past 1 years. Compared with patients without cuteexacerbation, the CAT score, SAS score and SDS score of patients suffered acute exacerbation were higher than and the difference wasstatistically significant (P<0.05). The quality of life among 66.4% patients with acute exacerbation was worsen at moderate and abovelevel with statistically significant (P<0.05). In addition, the prevalence of acute exacerbation in patients with anxiety and/or depressionwas higher than those without acute exacerbation, with statistically significant differences(P<0.05).Conclusion:Chronic obstructive pulmonaryexacerbation produced not only adverse effects on the quality of life but also on mental state of the patients with COPD.