Na(+)-dependent AIB transport by neuroblastoma cells. |
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| Authors: | A del Castillo-Olivares M A Medina |
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| Institution: | Ruprecht-Karls-Universit?t, Heidelberg, Germany. |
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| Abstract: | Na(+)-dependent amino isobutyric acid transport by two neuroblastoma cell lines with and without amplification of the oncogene N-myc is studied. Surprisingly, the contribution of system A is greater in the cell line showing no N-myc amplification. Preliminary data support a role for essential tyrosine and cysteine residues in the active center of the carriers, mainly in system A. |
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