On the identification by filtering techniques of a biologicaln-compartment model in which the transport rate parameters are assumed to be stochastic processes |
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Authors: | C Cobelli L M Morato |
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Institution: | 1. Laboratorio per Richerche di Dinamica dei Sistemi e di Elettronica, Biomedica del Consiglio Nazionale delle Ricerche, Padova, Italy 2. Istituto di Elettrotecnica e di Elettronica, Universit? di Padova, Italy
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Abstract: | In this paper biological compartmental models are considered which take into account the intrinsic randomness of the transport
rate parameters and their possible variability in time. An identification procedure is presented for the estimation of the
stochastic processes representing the transport rate parameters of a compartmental model from a noisy input-output experiment.
The problem is formulated in terms of nonlinear filtering. A simple model is discussed for the case in which the transport
rate parameters are independent of each other. The possibility of testing possible important features of the behavior of the
transport rate parameters is also evidenced. |
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Keywords: | |
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