High-Virulence Clone of Group B Streptococci Unable to Grow at High Temperatures Is Present in Serotypes Other Than Type III |
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| Authors: | Gerardo C. Palacios Maria N. Gonzalez Magdalena Beltran Jose L. Arredondo Javier Torres Fortino Solorzano |
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| Affiliation: | (1) Departamento de Infectologia and Unidad de Investigacion en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatria, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Cuauhtemoc 330 Colonia Doctores, Delegacion Cuauhtemoc, Mexico City, Mexico, 06720;(2) Departamento de Infectologia, Instituto Nacional de Perinatologia, Secretaria de Salud, Montes Urales 800, Colonia Lomas de Virreyes, Delegacion Miguel Hidalgo, Mexico City, Mexico, 11000 |
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| Abstract: | Highly virulent clonotypes of serotype III seem to cause much of the perinatal morbidity and mortality attributed to Streptococcus agalactiae (group B streptococci, GBS), One of these clonal types, designated the “high-virulence clone” (HVC), was identified by its inability to grow at 40°C in a chemically defined medium. In the present study, this inability to grow at high temperatures was used as a marker to identify HVC in a sample of 286 Mexican GBS isolates. Forty-three isolates (15%) were identified as belonging to this clone: 15 were invasive isolates, 33 were serotype III (77%), and 10 were of serotypes other than type III (23%). These results demonstrate that HVC is more prevalent in Mexico than previously reported and that this clone is not restricted to serotype III isolates. |
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