| 单核细胞趋化蛋白受体的研究进展 |
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| 引用本文： | 鲍荣辉,刘先哲.单核细胞趋化蛋白受体的研究进展[J].生命科学,2006,18(5):477-480. |
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| 作者姓名： | 鲍荣辉 刘先哲 |
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| 作者单位： | 三峡大学医学院,宜昌,443002 |
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| 基金项目： | 宜昌市科技发展计划资助项目(A04303-3) |
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| 摘 要： | 单核细胞趋化蛋白及其受体在机体免疫应答中(免疫调节、器官形成、调节造血和神经元通讯)发挥了重要作用,同时也广泛参与某些疾病的发病机制(动脉粥样硬化、感染炎症性疾病及肿瘤等)。因此,有关趋化性细胞因子的新理论和技术可为临床治疗某些疾病提供了新思路。本文简要地综述单核细胞趋化蛋白受体的生物学特性、生物学作用及对心血管疾病的影响作用。
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| 关 键 词： | 单核细胞趋化蛋白 受体 疾病 |
| 文章编号： | 1004-0374（2006）05-0477-04 |
| 收稿时间： | 2005-12-15 |
| 修稿时间： | 2006-04-14 |
Research progress of monocyte chemoattractant protein receptor |
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| BAO Rong-Hui,LIU Xian-Zhe.Research progress of monocyte chemoattractant protein receptor[J].Chinese Bulletin of Life Sciences,2006,18(5):477-480. |
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| Authors: | BAO Rong-Hui LIU Xian-Zhe |
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| Institution: | Medical College of China Three Gorges University, Yichang 443002, China |
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| Abstract: | Monocyte chemoattractant protein and their receptors in immunity reply (immunoloregulation, organogenesis, hematopoiesis and neuronal communication) have played important roles, and also widely participate in the pathogenesy of diseases (atherosclerosis, inflammatory, tumor, etc). Therefore, the new theory and the technology about chemokines may provide some new ways for clinical treatment of certain diseases. This review focuses on the biological charactoristics and functions of cc chemokine receptor (CCR), and its effects on the cardiovascular diseases. |
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| Keywords: | monocyte chemoattractant protein receptor disease |
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