Formation and remodeling of epithelial polarity

Polarity is a fundamental property of all eukaryotic cells that underlies many developmental processes. A recent EMBO workshop (March 27-31) organized by Thomas Lecuit, Norbert Perrimon, and Keith Mostov brought cell and developmental biologists together on the Mediterranean coast near Marseille, France, to share views on how epithelium polarity is established and remodeled during development and disease. Participants witnessed and celebrated the emerging convergence of intellectual and experimental approaches to address how individual cells acquire polarity and form polarized tissues in the context of developing embryos.