Translocation of proteins across archaeal cytoplasmic membranes |
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Authors: | Pohlschröder Mechthild Dilks Kieran Hand Nicholas J Wesley Rose R |
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Institution: | Department of Biology, University of Pennsylvania, 415 University Avenue, 201 Leidy Labs, Philadelphia, PA 19104-6018, USA. pohlschr@sas.unpenn.edu |
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Abstract: | All cells need to transport proteins across hydrophobic membranes. Several mechanisms have evolved to facilitate this transport, including: (i) the universally-conserved Sec system, which transports proteins in an unfolded conformation and is thought to be the major translocation pathway in most organisms and (ii) the Tat system, which transports proteins that have already obtained some degree of tertiary structure. Here, we present the current understanding of these processes in the domain Archaea, and how they compare to the corresponding pathways in bacteria and eukaryotes. |
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Keywords: | Sec system Tat system Protein translocation Archaea |
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