Cardiomyopathies and mitochondrial DNA mutations |
| |
| Authors: | Takeda Nobuakira |
| |
| Institution: | (1) Department of Internal Medicine, Aoto Hospital, Jikei University School of Medicine, Tokyo, Japan |
| |
| Abstract: | Our former studies concerning mitochondrial DNA mutations were reviewed in this article. A 7.4 kb deletion between the D-loop and ATPase 6 genes was detected in myocardial tissue obtained at autopsy from patients with myocardial infarction, diabetes mellitus and also patients treated with adriamycin. A case with diabetes mellitus and hypertrophic cardiomyopathy is demonstrated which revealed a point mutation from adenine to guanine at position 3243 within tRNALeu(UUR). |
| |
| Keywords: | mitochondrial DNA diabetes mellitus hypertrophic cardiomyopathy myocardial infarction adriamycin |
| 本文献已被 SpringerLink 等数据库收录！ |
