Quantitative target proteomics of chromosome 13 human blood plasma proteins |
| |
| Authors: | A. T. Kopylov E. V. Ilgisonis O. V. Tikhonova T. E. Farafonova S. E. Novikova V. G. Zgoda E. A. Ponomarenko A. V. Lisitsa A. A. Markin B. V. Morukov A. I. Grigoriev A. I. Archakov |
| |
| Affiliation: | 1.Orekhovich Institute of Biomedical Chemistry,Moscow,Russia;2.Institute of Biomedical Problems,Russian Academy of Sciences,Moscow,Russia |
| |
| Abstract: | Quantitative proteomic analysis of 50 blood plasma samples of healthy volunteers who underwent a comprehensive medical examination and were found eligible for space flights was performed. As a result of directed mass spectrometric analysis, signals for 128 proteins, which accounted for nearly 40% of the total number of chromosome 13 gene products, were detected. The analysis of interindividual variation of concentrations of chromosome 13 proteins showed the presence of a pool comprising 41 proteins with a low variation (CV < 30%), which can potentially be used as biomarkers. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
