Evolutionary Analysis of the Small Heat Shock Proteins in Five Complete Algal Genomes |
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Authors: | Elizabeth R Waters Ignatius Rioflorido |
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Institution: | (1) Department of Biology, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182-4614, USA |
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Abstract: | Small heat shock proteins (sHSPs) are chaperones that are crucial in the heat shock response but also have important nonstress
roles within the cell. sHSPs are found in all three domains of life (Bacteria, Archaea, and Eukarya). These proteins are particularly
diverse within land plants and the evolutionary origin of the land plant sHSP families is still an open question. Here we
describe the identification of 17 small sHSPs from the complete genome sequences of five diverse algae: Chlamydomonas reinhardtii, Cyanidioschyzon merolae, Ostreococcus lucimarinus, Ostreococcus tauri, and Thalassiosira pseudonana. Our analysis indicates that the number and diversity of algal sHSPs are not correlated with adaptation to extreme conditions.
While all of the algal sHSPs identified are members of this large and important superfamily, none of these sHSPs are members
of the diverse land plant sHSP families. The evolutionary relationships among the algal sHSPs and homologues from bacteria
and other eukaryotes are consistent with the hypothesis that the land plant chloroplast and mitochondrion sHSPs did not originate
from the endosymbionts of the chloroplast and mitochondria. In addition the evolutionary history of the sHSPs is very different
from that of the HSP70s. Finally, our analysis of the algal sHSPs sequences in light of the known sHSP crystal structures
and functional data suggests that the sHSPs possess considerable structural and functional diversity.
Electronic supplementary material The online version of this article (doi: ) contains supplementary material, which is available to authorized users.
Reviewing
Editor: Dr. Rüdiger Cerff |
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Keywords: | Heat shock hsp20 α -Crystallin Comparative genomics Gene family evolution Chlamydomonas reinhardtii Cyanidioschyzon merolae Thalassiosira pseudonana Ostreococcus |
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