|
|||||
|
|
Electron microscopy of functional ribosome complexes |
|
| Authors: | Frank Joachim |
| Institution: | Howard Hughes Medical Institute, Health Research, Inc, at the Wadsworth Center, and Department of Biomedical Sciences, State University of New York at Albany, Empire State Plaza, Albany, NY 12201-0509, USA. joachim@wadsworth.org |
| Abstract: | Cryoelectron microscopy has made a number of significant contributions to our understanding of the translation process. The method of single-particle reconstruction is particularly well suited for the study of the dynamics of ribosome-ligand interactions. This review follows the events of the functional cycle and discusses the findings in the context provided by the recently published x-ray structures. |
| Keywords: | translation tRNA EF‐G three‐dimensional reconstruction molecular machines |
| 本文献已被 PubMed 等数据库收录！ | |