褐色脂肪组织及其产热研究进展

褐色脂肪组织(BAT)及非颤抖性产热(NST)是生理生态学和生物能学研究中的一个热点。国外学者已从解剖学、组织学、生理学、细胞学及生物化学等各个方面,从细胞,亚细胞、分子及线粒体水平上对BAT及其产

Brown Adipose Tissue and Its Thermogenesis: A Review.

Brown Adipose Tissue(BAT) is quite distinct from common white one in function and structure.Its major function is to generate heat under cold stress (nonshivering thermogenesis, NST), burn excess calories for preventing obesity (diet-induced thermogenesis, DIT) and raise body temperature for combating infection, etc.. Factors influencing the amount and activity of BAT are numerous, but the important ones are body size, age,ambient temperature, photoperiod, diet, reproductive stage, and so on. Researches on BAT and NST have important significance in understanding the cold seasonal acclimatization of small mammals and in human physiology and medicine (e.g. aetiology of obesity).