|
|||||
|
|
Close encounters between active genes in the nucleus |
|
| Authors: | Chien-Hui?Chuang |
| Institution: | (1) Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, 601 South Goodwin Avenue, Urbana, IL 61801, USA; |
| Abstract: | A recent paper demonstrates that coregulated genes on different chromosomes show surprisingly high frequencies of colocalization within the nucleus; this complements similar results found previously for genes localized tens of megabases apart on a single chromosome. Colocalization could be related to the earlier observation of active genes associating with foci where RNA polymerase II is concentrated. |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |