| 植物Hippo信号通路研究进展 |
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| 引用本文： | 张平平,佟鑫,张天乐,黎子琛,龚清秋.植物Hippo信号通路研究进展[J].遗传,2017,39(7):568-575. |
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| 作者姓名： | 张平平 佟鑫 张天乐 黎子琛 龚清秋 |
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| 作者单位： | 南开大学生命科学学院,天津市蛋白质科学重点实验室,天津 300071 |
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| 基金项目： | 国家自然科学基金项目(31671419);南开大学中央高校基本科研业务费(63161201) |
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| 摘 要： | 植物器官大小如何决定是发育生物学的基本问题之一。Hippo信号通路是动物中最重要的负调控器官大小的信号通路。近期研究表明,植物中可能也存在Hippo信号通路。本文回顾了植物中已经发现的两个Hippo信号通路的核心蛋白——Ste20/Hippo同源蛋白SIK1与MOB1/Mats同源蛋白MOB1,着重论述了SIK1和MOB1在调控植物生长发育中的作用,并对未来建立一条完整的植物Hippo信号通路进行了展望。
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| 关 键 词： | Hippo信号通路 SIK1 MOB1 器官大小 细胞分裂 细胞延展 |
| 收稿时间： | 2017-02-28 |
The emerging Hippo signaling pathway in plants |
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| Institution: | Tianjin Key Laboratory of Protein Sciences, College of Life Sciences, Nankai University, Tianjin 300071, China |
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| Abstract: | How the organ size is determined is a fundamental question in developmental biology. The metazoan Hippo signaling pathway is well established to negatively regulate organ sizes. Recent studies in plants have started to shape an emerging Hippo signaling pathway. In this review, we summarize the studies in the past decade on the two known components of plant Hippo signaling pathway, the Ste20/Hippo homolog SIK1, and the MOB1/Mats homolog MOB1, with a focus on their developmental functions. Then we envision future discoveries that may shape a complete Hippo signaling pathway in plants. |
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| Keywords: | Hippo signaling pathway serine/threonine kinase 1 (SIK1) MOB1 organ size cell division cell expansion |
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