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| 鲤鱼微卫星突变速率和模式(英文) | |
| 引用本文： | Zhang Y,Lu CY,Cao DC,Xu P,Wang S,Li HD,Zhao ZX,Sun XW. 鲤鱼微卫星突变速率和模式(英文)[J]. 动物学研究, 2010, 31(5): 561-564. DOI: 10.3724/SP.J.1141.2010.05561 |
| 作者姓名： | Zhang Y Lu CY Cao DC Xu P Wang S Li HD Zhao ZX Sun XW |
| 作者单位： | 1. 中国水产科学研究院水产应用基因组研究中心,北京,100141;黑龙江水产研究所,北方鱼类生物工程育种重点开放实验室,黑龙江,哈尔滨,150070 2. 黑龙江水产研究所,北方鱼类生物工程育种重点开放实验室,黑龙江,哈尔滨,150070 3. 中国水产科学研究院水产应用基因组研究中心,北京,100141 |
| 基金项目： | 公益性行业科研专项:水产分子育种共性技术的建立与应用(200903045); 中央级公益性科研院所基本科研业务费专项资金项目(2010C016) |
| 摘 要： | 利用150个微卫星分子标记在F1代家系的基因型分析过程中,共有27600个等位基因从亲本向子代传递,其中在5个微卫星座位上检测到6个突变的等位基因。对突变的等位基因数目进行统计分析后得出:鲤鱼平均每个世代每个微卫星座位的突变速率为2.53×10-4。在发现突变的5个位点中,经测序发现,突变序列中插入1个以上的重复单元就导致了突变的发生。这些突变表明,鲤鱼的微卫星突变没有遵循严格的渐变突变模型(stepwise mutation model,SMM)。该文关于鲤鱼微卫星突变速率和模式的研究将会对统计鲤鱼有效群体的统计提供有效参数。 |
| 关 键 词： | 突变速率 突变模式 鲤鱼 |
Rates and patterns of microsatellite mutations in common carp (Cyprinus carpio L.) |
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| Zhang Yan,Lu Cui-Yun,Cao Ding-Chen,Xu Peng,Wang Shu,Li Heng-De,Zhao Zi-Xia,Sun Xiao-Wen. Rates and patterns of microsatellite mutations in common carp (Cyprinus carpio L.)[J]. Zoological Research, 2010, 31(5): 561-564. DOI: 10.3724/SP.J.1141.2010.05561 | |
| Authors: | Zhang Yan Lu Cui-Yun Cao Ding-Chen Xu Peng Wang Shu Li Heng-De Zhao Zi-Xia Sun Xiao-Wen |
| Affiliation: | ZHANG Yan1,2,LU Cui-Yun2,CAO Ding-Chen2,XU Peng1,WANG Shu1,LI Heng-De1,ZHAO Zi-Xia1,SUN Xiao-Wen1,(1. The Centre for Applied Aquatic Genomics,Chinese Academy of Fishery Sciences,Beijing 100141,China,2. Heilongjiang Fisheries Research Institute,Chinese Academy of Fisheries Sciences,Harbin 150040,China) |
| Abstract: | During genotyping 150 microsatellites in a Fi family of common carp, six mutations were found at five microsatellite loci. The overall mutation rate of common carp microsatellites was 2.53 ～ 10-4 per locus per generation. At five loci, mutations increased the length of alleles by at least one repeat unit, suggesting mutations at microsatellite loci in common carp do not follow strict stepwise mutation model. The data on mutation rates and patterns can facilitate population genetics studies, and provide useful parameters for estimating a long-term effective population size of common carp. |
| Keywords: | Mutation rate Mutation pattern Common carp |
| 本文献已被 CNKI 万方数据 PubMed 等数据库收录！ | |