Anti-trichomonal IgA antibodies in trichomoniasis before and after treatment |
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Authors: | P. Sharma N. Malla I. Gupta N. K. Ganguly R. C. Mahajan |
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Affiliation: | (1) Department of Parasitology, Postgraduate Institute of Medical Education and Research, 160 012 Chandigarh, India;(2) Department of Obstetrics, Postgraduate Institute of Medical Education and Research, 160 012 Chandigarh, India;(3) Department of Experimental Medicine, Postgraduate Institute of Medical Education and Research, 160 012 Chandigarh, India |
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Abstract: | Anti-trichomonal IgA antibodies were estimated by enzyme-linked immunosorbent assay (ELISA) in serum and vaginal secretions of 25 symptomatic and 25 asymptomaticTrichomonas vaginalis positive patients before and after treatment and in 25 age-matched controls. Significantly higher levels of antitrichomonad IgA antibodies were found inT. vaginalis positive patients when compared to control subjects, especially in vaginal secretions. In addition, a significant decrease in these antibodies was observed after treatment, which was more pronounced in vaginal secretions. It seems that anti-trichomonal IgA antibodies in serum and more so in vaginal secretions are directly related to and specific to the presence ofT. vaginalis in the urogenital tract. |
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