Synthesis and antiviral activity of L-2'-deoxy-2'-up-fluoro-4'-thionucleosides. |
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Authors: | L S Jeong H R Moon S J Yoo S N Lee H D Kim M W Chun |
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Affiliation: | College of Pharmacy, Ewha Womans University, Seoul, Korea. |
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Abstract: | L-2'-Deoxy-2'-up-fluoro-4'-thionucleosides were efficiently synthesized from D-xylose via L-4-thioarabitol derivative as a key intermediate and evaluated for antiviral activities against HIV-1, HSV-1,2 and HBV. |
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