Simian Tumour Virus Proliferation in Inoculated Macaca mulatta |
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| Authors: | DONALD L. FINE ELIZABETH W. KINGSBURY MARION G. VALERIO MARY T. KUBICEK JOHN C. LANDON HARISH C. CHOPRA |
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| Affiliation: | 1.Bionetics Research Laboratories,Kensington;2.National Cancer Institute,Bethesda |
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| Abstract: | AN oncorna-type virus (M-PMV) was detected in a spontaneous breast tumour of a female rhesus monkey1,2. This virus is morphologically and biochemically similar to oncogenic RNA viruses of other species3–5. Using in vitro tissue culture assays and electron microscopy we have observed proliferation of infectious virus in hyperplastic lymph nodes of M-PMV inoculated infant rhesus monkeys. |
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