Studies on gangliosides of goldfish brain

Abstract— Purified gangliosides from goldfish brain have been separated on thin layer chromatography. Incorporation of radioactivity into gangliosides from intracranially- injected [³H]galactose was not affected by concentrations of puromycin (170 μg intra- cranially) known to exert behavioural effects. Puromycin (500 μg intracranially) inhibited the incorporation of radiolabelled galactose into infant rat brain gangliosides, a result which confirms a previous report in the literature.